Overview
Contains contributions by leading international researchers
Encourages collaboration by basic scientists and clinicians
Of interest to those involved in drug development
Includes supplementary material: sn.pub/extras
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (17 chapters)
-
Introduction
-
Section II
Keywords
About this book
Chemokine Receptors and NeuroAIDS: Beyond the Co-receptor Function and Links to Other Neuropathologies focuses on unresolved or emerging issues concerning the role of chemokine receptors in neuronal injury and HIV neuropathology, including their ability to regulate fundamental neuronal and glial functions and their role in neurovirulence and neurotoxicity. Although the importance of these molecules in the CNS physiology and pathology is now apparent, these issues are still matter of debate, and further research is required to design effective pharmacological agents that specifically target the brain chemokine system without major side effects.
To this end, specific topics have been selected and are reviewed by international experts within the basic science/medical community. This book encourages investigation in the most controversial areas and fosters interaction between clinicians and basic scientists. The book also increases awareness about differences in disease progression among different parts of the world as well as selected patient populations, which may also help identifying novel therapeutic strategies.
Editors and Affiliations
About the editor
About the Editor:
Olimpia Meucci, MD, PhD is a Professor of Pharmacology and Physiology & Microbiology and Immunology at Drexel University College of Medicine in Philadelphia, PA. Since her seminal discovery about the regulation of neuronal signaling by chemokines, her research has primarily focused on the physio-pathological roles of this important class of neuroimmune modulators in the central nervous system and their involvement in neuroAIDS. These studies have significantly contributed to current understanding of the cellular and molecular mechanisms of HIV-related neuropathology including the interaction of the chemokine system with drug of abuse, namely opiates, which continues to be a major area of investigation in the Meucci lab.
Bibliographic Information
Book Title: Chemokine Receptors and NeuroAIDS
Book Subtitle: Beyond Co-Receptor Function and Links to Other Neuropathologies
Editors: Olimpia Meucci
DOI: https://doi.org/10.1007/978-1-4419-0793-6
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag New York 2010
Hardcover ISBN: 978-1-4419-0792-9Published: 24 December 2009
Softcover ISBN: 978-1-4899-8487-6Published: 28 November 2014
eBook ISBN: 978-1-4419-0793-6Published: 02 December 2009
Edition Number: 1
Number of Pages: XVI, 412
Topics: Neurosciences, Virology, Pharmacology/Toxicology, Infectious Diseases