Addiction Medicine

1. Front Matter

   Pages i-xxix

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2. History, Perspectives, Epidemiology, Diagnosis, and Classification

   1. Front Matter

      Pages 1-1

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   2. Emerging Health Perspectives

      • H. Westley Clark, Linda Hutchings

      Pages 3-22

   3. The Epidemiology of Alcohol and Drug Disorders

      • Deborah Hasin, Katherine Keyes

      Pages 23-49

   4. United States Federal Drug Policy

      • Angela Hawken, Jonathan D. Kulick

      Pages 51-73

   5. Historical Perspectives of Addiction

      • Howard I. Kushner

      Pages 75-93

   6. Diagnosis and Classification of Substance Use Disorders

      • John B. Saunders, Noeline C. Latt

      Pages 95-113

3. Behavioral Theories for Addiction

   1. Front Matter

      Pages 115-115

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   2. Drug Reinforcement in Animals

      • Wendy J. Lynch, Scott E. Hemby

      Pages 117-128

   3. Role of the Human Laboratory in the Development of Medications for Alcohol and Drug Dependence

      • John D. Roache

      Pages 129-157

   4. Conditioning of Addiction

      • M. Foster Olive, Peter W. Kalivas

      Pages 159-178

4. Genetic and Other Biological Theories for Addiction

   1. Front Matter

      Pages 179-179

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   2. Mouse Models: Knockouts/Knockins

      • Weihua Huang, Wenhao Xu, Ming D. Li

      Pages 181-199

   3. Vulnerability to Substance Abuse

      • George R. Uhl, Tomas Drgon, Catherine Johnson, Qing-Rong Liu

      Pages 201-223

   4. The Pharmacogenomics of Addiction

      • David Goldman

      Pages 225-236

   5. Metabolomics in Drug Response and Addiction

      • Raihan K. Uddin, Shiva M. Singh

      Pages 237-253

   6. Neurobiological Basis of Drug Reward and Reinforcement

      • David M. Lovinger

      Pages 255-281

   7. Neurobehavioral Toxicology of Substances of Abuse

      • Martin A. Javors, Thomas S. King, Brett C. Ginsburg, Lisa R. Gerak

      Pages 283-331

   8. Animal Models of Drug Dependence: Motivational Perspective

      • George F. Koob

      Pages 333-357

   9. Novel Methodologies: Proteomic Approaches in Substance Abuse Research

      • Scott E. Hemby, Wendy J. Lynch, Nilesh S. Tannu

      Pages 359-378

The spectrum of addiction disorders presents practitioners with numerous challenges—among them the widening gap between a growing evidence base and the translation of this knowledge into treatment outcomes. Addiction Medicine addresses this disconnect, clearly explaining the role of brain function in drug taking and other habit-forming behaviors, and applying this biobehavioral framework to the delivery of evidence-based treatment. Its state-of-the-art coverage provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding). Current behavioral and medical therapies are discussed in depth, and the book’s close attention to social context gives readers an added lens for personalizing treatment. An international panel of expert contributors offers the most up-to-dateinformation on: Diagnosis and classification Neurobiological and molecular theories of addiction Behavioral concepts of addiction Clinical aspects of addiction to a wide range of substances, including opiates, stimulants, sedatives, hallucinogens, alcohol, nicotine, and caffeine Science-based treatment options: pharmacotherapy, pharmacogenetics, potential vaccines, brief and compliance-enhancing interventions, cognitive behavioral treatment, behavioral management, and other psychosocial interventions Behavioral addictions—including compulsive eating, Internet messaging, and hypersexuality—and their treatment Addiction in specific populations, including adolescents, the elderly, pregnant women, and health care professionals Legal, disability, and rehabilitation issues At once comprehensive and integrative, Addiction Medicine is an essential text and a practice-expanding tool for psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners.

• Addiction
• Addiction Disorders
• alcoholics anonymous
• alcoholism
• drug abuse
• drug addiction
• drug-taking behavior
• neurobiology of drug abuse
• psychophysiology of addiction
• psychophysiology of drug abuse
• substance abuse

“The authors integrate all the scientific knowledge and treatment experiences in a scientifically based, holistic approach and give us a clear message how to treat them. … I recommend this textbook as an unavoidable reading and great help for all experts dealing with the problems from the field of addiction medicine.” (Assist. Prof. Ana Matošić, Alcoholism and Psychiatry Research, Vol. 51 (2), 2015)

“This comprehensive, detailed book presents the most up-to-date scientific research and evidence-based studies on addictions to substances as well as behavioral addictions. … The book is designed for psychiatrists, general physicians/family practitioners, psychologists, pharmacologists, social workers, drug counselors, and trainees as well as healthcare workers who deal with patients with addictions in their clinical practices. … This is an impressive, thorough, and detailed reference on addiction medicine.” (Michael Easton, Doody’s Review Service, August, 2012)

• , Depts Psychiat & Neurobehav Sciences, Me, University of Virginia, Charlottesville, USA

  Bankole A. Johnson

Bankole A. Johnson, D.Sc., M.D., is a Professor of Psychiatry and Neurobehavioral Sciences, Medicine, and Neuroscience at the University of Virginia, Charlottesville, VA, USA.

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