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Programmed Cell Death in Cancer Progression and Therapy

  • Book
  • © 2008

Overview

  • Up-to-date and comprehensive description of Molecular Mechanism of PCD in Cancer Progression and Therapy
  • Up-to-date and comprehensive information regarding the current therapeutic strategies that utilize PCD
  • Detailed indication of the utility of PCD in future cancer therapy
  • Chapters on the current and future of RNA interference in therapeutics and Pathways involved in Stem Cell Survival and Death

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 615)

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Table of contents (15 chapters)

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About this book

Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. With the discovery of key mechanisms that are involved in mediating PCD and in promoting resistance to therapy, design of therapeutic approaches for promoting tumor-selective cell death has risen dramatically. With this book, we give a comprehensive overview of the mechanisms that are involved in mediating and regulating PCD in cancer. We also provide a detailed indication of the utility of PCD in cancer therapy. This book will be a valuable resource for researchers investigating the role of PCD in cancer and other diseases, researchers investigating the molecular mechanism of chemotherapeutic agents and drug-resistance in cancer and for physicians using chemotherapeutic agents. Additionally, this book will be a important educational source for PhD students specializing in cell biology, immunology and MD students interested in Oncology and Cancer Therapeutics.

Reviews

From the reviews:

"Programmed cell death (PCD) is an intriguing term that was introduced by Richard Lockshin nearly 45 years ago. … this book is about PCD with intense focus on apoptosis and the exploitation of PCD for treating cancer. … All chapters are well edited and thoroughly referenced. The nicety of the book is the use of numerous color figures. In my opinion, both scientists and clinicians, experienced or beginning, will profit from a thoughtful reading of Programmed Cell Death in Cancer Progression and Therapy." (A. A. Philchenkov, Biochemistry (Moscow), Vol. 74 (4), 2009)

Authors and Affiliations

  • Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, USA

    Roya Khosravi-Far

  • Center for Advanced Biotechnology and Medicine; Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, USA

    Eileen White

  • Cancer Institute of New Jersey, New Brunswick, USA

    Eileen White

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