Overview
- A key reference summarizing the state-of-the-art in creatine and creatine kinase research
- An authoritative volume compiled by outstanding experts in the field
- A must-read for understanding the links between creatine metabolism and neuroprotection as well as neurodegenerative disease
- A book that aims to lay the foundation for a next boost in research on the pleiotropic functions of creatine and creatine kinase
- A text that sets the stage for "systems biology" of creatine and creatine kinase
Part of the book series: Subcellular Biochemistry (SCBI, volume 46)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (16 chapters)
-
Front Matter
-
Back Matter
Keywords
About this book
Although creatine was discovered already in the 1830s, it is only in recent years that its crucial role for human health and general well-being has been increasingly realized and appreciated. A number of beneficial health effects have been ascribed to oral creatine supplementation, such as neuroprotective, ergogenic, anti-diabetic, anti-inflammatory, antiviral, or antitumor effects. Creatine may even improve memory and intelligence. In the present book, emphasis is placed on the intricate interplay between creatine and creatine kinase function on one hand, and proper brain function, neurodegenerative disease and/or neuroprotection on the other hand. The book also elaborates on the recently identified inborn errors of creatine biosynthesis and transport, the so-called cerebral creatine deficiency syndromes. The clinical hallmarks of these disorders are mental retardation, epilepsy, autistic-like behaviour, and speech and language delay. In addition, the muscle growth- and strength-promoting effects, the pharmacokinetics and the safety of oral creatine supplementation are discussed. Finally, the present book outlines the emerging "systems biology" approaches for understanding the pleiotropic effects of creatine and creatine kinase, and hypothesizes on the most promising and influential future avenues of research towards creatine-based nutritional strategies for the prevention of neurological disease, and for improving the quality of life in general.
Editors and Affiliations
Bibliographic Information
Book Title: Creatine and Creatine Kinase in Health and Disease
Editors: Gajja S. Salomons, Markus Wyss
Series Title: Subcellular Biochemistry
DOI: https://doi.org/10.1007/978-1-4020-6486-9
Publisher: Springer Dordrecht
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media B.V. 2007
Hardcover ISBN: 978-1-4020-6485-2Published: 14 November 2007
Softcover ISBN: 978-90-481-7652-6Published: 20 November 2010
eBook ISBN: 978-1-4020-6486-9Published: 16 October 2007
Series ISSN: 0306-0225
Series E-ISSN: 2542-8810
Edition Number: 1
Number of Pages: XVIII, 354
Topics: Neurology, Medical Biochemistry, Human Genetics, Quality of Life Research