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  • © 2005

Application of Apoptosis to Cancer Treatment

Authors:

  • Due to new insights, it is now becoming possible to apply the discoveries in the field of apoptosis (programmed cell death) to treating cancer patients.
  • This book presents an update of the most recent developments in this explosive field

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-vii
  2. Calcium Signaling and Apoptosis Resistance of Cancer Cells

    • Natalia Prevarskaya, Roman Skryma, Yaroslav Shuba
    Pages 29-49
  3. Cell Clearance and Cancer

    • Bengt Fadeel
    Pages 51-84
  4. Targeting Oncogenes Which Regulate Apoptosis

    • Andrew C. Phillips
    Pages 117-144
  5. Targeting Cyclins to Cause Cancer Cell Apoptosis

    • Supama Mazumder, Dragos Plesca, Alexandru Almasan
    Pages 145-177
  6. Apoptosis Induction By Tumor- Targeted Toxins

    • Andrew Thorburn
    Pages 179-187
  7. Targeting Cell-Death Pathways in Multiple Myeloma: Therapeutic Implications

    • Dharminder Chauhan, Kenneth Anderson
    Pages 189-208
  8. Cephalostatin 1-Induced Apoptosis in Tumor Cells

    • Verena M. Dirsch, Angelika M. Vollmar
    Pages 209-221
  9. Hamlet; A Novel Tool to Identify Apoptotic Pathways in Tumor Cells

    • Caroline Düringer, Oskar Hallgren, Lotta Gustafsson, Jenny Petterson, Ann-Kristin Mossberg, Taras Manilov et al.
    Pages 223-245
  10. Cancer Immunotherapy: On the Trail of a Cure?

    • Thomas S. Griffith, Troy J. Kemp, Aaron T. Ludwig, Jill M. Moore, Rebecca L. VanOosten
    Pages 247-270
  11. Histone Deacetylase Inhibitors as a Treatment of Trail-Resistant Cancers

    • Jiri Neuzill, Ladislav Andera, Brian Gabrielli
    Pages 271-291
  12. Basis of Cell Kill Following Clinical Radiotherapy

    • Oliver Faulhaber, Robert G Bristow
    Pages 293-320
  13. Imaging of Apoptotic Cells in vivo

    • Juhana Hakumäki
    Pages 321-339
  14. Apoptosis-Inducing Anticancer Drugs in Clinical Trials

    • Wei Hu, John J. Kavanagh
    Pages 341-364
  15. Back Matter

    Pages 365-370

About this book

Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body. Research is also directed to investigate why the cancer cells sometimes lose the ability to undergo apoptosis after a certain period of time and methods are being developed to reactivate this cell death process. This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients.

Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS. He brings together a collection of papers written by the world’s leading experts in these fields.

Authors and Affiliations

  • The Netherlands Cancer Institute, Amsterdam, The Netherlands

    Mels Sluyser

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access