Overview
- Editors:
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David M. Webster
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Southern Cross Molecular, Bath, UK
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Table of contents (18 protocols)
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- Desmond G. Higgens, William R. Taylor
Pages 1-18
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- Chris P. Ponting, Ewan Birney
Pages 53-69
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- Burkhard Rost, Chris Sander
Pages 71-95
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- Roberto Sánchez, Andrej Šali
Pages 97-129
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- Boris A. Reva, Alexei V. Finkelstein, Jeffrey Skolnick
Pages 155-174
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- Enoch S. Huang, Ram Samudrala, Britt H. Park
Pages 223-245
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- Marc De Maeyer, Johan Desmet, Ignace Lasters
Pages 265-304
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- Mark S. P. Sansom, Leo Davison
Pages 325-347
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- Johan Desmet, Marc De Maeyer, Jan Spriet, Ignace Lasters
Pages 359-376
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- Haim J. Wolfson, Ruth Nussinov
Pages 377-397
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- Michael J. E. Sternberg, Henry A. Gabb, Richard M. Jackson, Gidon Moont
Pages 399-415
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Back Matter
Pages 417-422
About this book
The number of protein sequences grows each year, yet the number of structures deposited in the Protein Data Bank remains relatively small. The importance of protein structure prediction cannot be overemphasized, and this volume is a timely addition to the literature in this field. Protein Structure Prediction: Methods and Protocols is a departure from the normal Methods in Molecular Biology series format. By its very nature, protein structure prediction demands that there be a greater mix of theoretical and practical aspects than is normally seen in this series. This book is aimed at both the novice and the experienced researcher who wish for detailed inf- mation in the field of protein structure prediction; a major intention here is to include important information that is needed in the day-to-day work of a research scientist, important information that is not always decipherable in scientific literature. Protein Structure Prediction: Methods and Protocols covers the topic of protein structure prediction in an eclectic fashion, detailing aspects of pred- tion that range from sequence analysis (a starting point for many algorithms) to secondary and tertiary methods, on into the prediction of docked complexes (an essential point in order to fully understand biological function). As this volume progresses, the authors contribute their expert knowledge of protein structure prediction to many disciplines, such as the identification of motifs and domains, the comparative modeling of proteins, and ab initio approaches to protein loop, side chain, and protein prediction.
Reviews
"The organization of this book is excellent. Eighteen chapters lead the reader through the entire process....Many of the authors are, in fact, the developers of some commonly used methods and offer a first-hand introduction to their software....The emphasis is on providing a practical handbook...most chapters contain detailed tutorials and worked-through examples that give a real-life flavor to the explanations."- Journal of American Chemical Society
"The book is a collection of 18 review articles, many written by distinguished experts in their field, providing an overview of the major aspects of protein structure prediction. About half of the articles deal with specific software packages, many of which are free to academic users, where the author of the software discussed....a useful reference to address for anyone thinking of dipping their toes into this exciting field." - Biochemistry and Molecular Biology Education
Editors and Affiliations
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Southern Cross Molecular, Bath, UK
David M. Webster
