Considerable effort and time is allocated to introducing cell culture and fermentation technology to undergraduate students in academia, generally through a range of courses in industrial biotechnology and related disciplines. Similarly, a large number of textbooks are available to describe the appli- tions of these technologies in industry. However, there has been a general lack of appreciation of the significant developments in downstream processing and isolation technology, the need for which is largely driven by the stringent re- latory requirements for purity and quality of injectable biopharmaceuticals. This is particularly reflected by the general absence of coverage of this s- ject in many biotechnology and related courses in educational institutions. For a considerable while I have felt that there is increasing need for an introductory text to various aspects of downstream processing, particularly with respect to the needs of the biopharmaceutical and biotechnology ind- try. Although there are numerous texts that cover various aspects of protein purification techniques in isolation, there is a need for a work that covers the broad range of isolation technology in an industrial setting. It is anticipated that Downstream Processing of Proteins: Methods and Protocols will play a small part in filling this gap and thus prove a useful contribution to the field. It is also designed to encourage educational strategists to broaden the coverage of these topics in industrial biotechnology courses by including accounts of this important and rapidly developing element of the industrial process.

Reviews

"The contributors are almost exclusively directly and actively involved in practical process applications on a day-to-day basis, which adds considerable credibility to the overall presentation. ... the editor succeeds in his aim, producing a straightforward and uncomplicated directory of the integrated steps necessary to bring a product to market." - Chromatographia

"This valuable book is the result of collective work of mostly corporate authors with important experience in downstream processing of proteins in industrial and biotechnological environments....It may be good textbook in industrial biotechnology courses especially because of ample protocols given in this book....The simplicity and clarity of the chapters is contains could be also of a great advantage for food science, which would certainly need to have good bench book....I would recommend highly this unpretentious but highly valuable book also to the readers active in our field."-Nahrung/Food

"a worthwhile addition to the reference collections of special and academic libraries that serve scientists interested in the study and isolation of medical products from natural materials."-E-streams Electronic Book Reviews

Editors and Affiliations

Medeva Pharma Ltd., Liverpool, UK

Mohamed A. Desai

Bibliographic Information

Book Title: Downstream Processing of Proteins
Book Subtitle: Methods and Protocols
Editors: Mohamed A. Desai
Series Title: Methods in Biotechnology
DOI: https://doi.org/10.1007/978-1-59259-027-8
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Hardcover ISBN: 978-0-89603-564-5Published: 31 March 2000
Softcover ISBN: 978-1-61737-075-5Published: 19 November 2010
eBook ISBN: 978-1-59259-027-8Published: 05 February 2008
Series ISSN: 1940-6061
Series E-ISSN: 1940-607X
Edition Number: 1
Number of Pages: IX, 229
Topics: Biotechnology

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Table of contents (16 protocols)

Front Matter

Back Matter

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