Skip to main content
SpringerLink
Log in

Advances in Allogeneic Hematopoietic Stem Cell Transplantation

  • Book
  • © 1999

Overview

Editors:
  1. Richard K. Burt

    1. Northwestern University Medical Center, Chicago, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Mary M. Brush

    1. Northwestern University Medical Center, Chicago, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Cancer Treatment and Research (CTAR, volume 101)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Allogeneic Peripheral Blood Stem Cell Transplantation for Hematologic Diseases

    • Martin Körbling
    Pages 1-23

  3. Unrelated Donor Marrow Transplantation for Treatment of Childhood Hematologic Malignancies-Effect of HLA Disparity and Cell Dose

    • Ann E. Woolfrey, Claudio Anasetti, Effie W. Petersdorf, Paul J. Martin, Jean E. Sanders, John A. Hansen
    Pages 25-51

  4. Haploidentical Transplantation

    • P. Jean Henslee-Downey
    Pages 53-77

  5. Umbilical Cord Blood Hematopoietic Stem Cell Transplantation

    • E. Gluckman, V. Rocha, C. L. Chastang
    Pages 79-96

  6. Non Myeloablative “Mini Transplants”

    • Sergio Giralt, Issa Khouri, Richard Champlin
    Pages 97-108

  7. Allogeneic Hematopoietic Stem Cell Transplantation in Recipients of Cellular or Solid Organ Allografts

    • Norma S. Kenyon, Maria Chatzipetrou, Andreas Tzakis, Joshua Miller, Rodolfo Alejandro, Camillo Ricordi
    Pages 109-132

  8. Allogeneic Peripheral Blood Progenitor Cell Transplantation in Solid Tumors

    • Naoto T. Ueno, Gabriel N. Hortobagyi, Richard E. Champlin
    Pages 133-156

  9. Hematopoietic Stem Cell Transplantation of Multiple Sclerosis, Rheumatoid Arthritis, and Systemic Lupus Erythematosus

    • Richard K. Burt, Ann Traynor, William Burns
    Pages 157-184

  10. Advances in the Control of Cytomegalovirus Disease in Bone Marrow Transplant Patients

    • William H. Burns
    Pages 185-201

  11. Adoptive Immunotherapy for EBV-Associated Malignancies

    • Kenneth G. Lucas, J. Christian Barrett
    Pages 203-232

  12. Adoptive Immunotherapy Using Donor Leukocyte Infusions to Treat Relapsed Hematologic Malignancies after Allogeneic Bone Marrow Transplantation

    • William R. Drobyski
    Pages 233-266

  13. Clinical Use of Irradiated Donor Lymphocytes in Bone Marrow Transplantation

    • Alan M. Ship, Edmund K. Waller
    Pages 267-282

  14. Dendritic Cells and their Clinical Applications

    • D. N. J. Hart, G. J. Clark
    Pages 283-310

  15. Engineering Hematopoietic Grafts Using Elutriation and Positive Cell Selection to Reduce GVHD

    • Stephen J. Noga
    Pages 311-330

  16. Monoclonal Antibody and Receptor Antagonist Therapy for GVHD

    • James L. M. Ferrara, Ernst Holler, Bruce Blazar
    Pages 331-368

  17. Adoptive Immunotherapy for Leukemia: Donor Lymphocytes Transduced with the Herpes Simplex Thymidine Kinase Gene

    • Charles J. Link Jr., Ann Traynor, Tatiana Seregina, Richard K. Burt
    Pages 369-375

  18. Clinical Application of Hematopoietic Stem Cell Culture and Expansion

    • Stephen G. Emerson, Patricia D. Conrad.
    Pages 377-388

  19. New Cytokines and their Clinical Application

    • Ian K. McNiece
    Pages 389-405

  20. Back Matter

    Pages 407-414
    Download chapter PDF
Back to top

Keywords

About this book

The field of hematopoietic stem cell transplantation is rapidly evolving. Realization that hematopoietic stem cells give rise to the immune compartment has resulted in clinical trials of hematopoietic stem cell transplantation for patients with autoimmune diseases. Allogeneic hematopoietic transplants are a form of adoptive immunotherapy resulting in beneficial graft versus tumor effects. Large numbers of hematopoietic cells can be collected with ease. Therefore, a renewable source of cells for ex vivo genetic manipulations is readily available. Multiple trials combining hematopoietic transplants and gene therapy are in progress. One such application is the infusion of allogeneic lymphocytes containing a suicide gene to abort graft versus host disease. Hematopoietic stem cell transplantation is in reality the clinical and practical application of cellular therapy. Hematopoietic transplant physicians are by design or by practical application evolving into cell and gene therapy specialists. The excitement and enthusiasm in hematopoietic transplantation is that it offers a door to the future. A future not of drugs or titrating poisonous chemotherapy but rather of cellular and gene therapy. 1 ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR HEMATOLOGIC DISEASES Martin Korbling University o/Texas MD. Anderson Cancer Center, Houston, Texas 77030 INTRODUCTION Circulating hematopoietic stem cells have emerged as an alternative to bone marrow (BM) stem cells for allografting. For many years the reconstitutive potential of circulating stem cells was questioned; peripheral blood stem cells (PBSC) were even characterized a waste product (1).

Editors and Affiliations

  • Northwestern University Medical Center, Chicago, USA

    Richard K. Burt, Mary M. Brush

Bibliographic Information

  • Book Title: Advances in Allogeneic Hematopoietic Stem Cell Transplantation

  • Editors: Richard K. Burt, Mary M. Brush

  • Series Title: Cancer Treatment and Research

  • DOI: https://doi.org/10.1007/978-1-4615-4987-1

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1999

  • Hardcover ISBN: 978-0-7923-7714-6Published: 29 February 2000

  • Softcover ISBN: 978-1-4613-7264-6Published: 29 October 2012

  • eBook ISBN: 978-1-4615-4987-1Published: 28 November 2012

  • Series ISSN: 0927-3042

  • Series E-ISSN: 2509-8497

  • Edition Number: 1

  • Number of Pages: XI, 414

  • Topics: Oncology, Cancer Research

Publish with us

Policies and ethics

Back to top

Search

Navigation