Overview
- Editors:
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Daphne Kamely
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Research and Laboratory Management, U.S. Army, USA
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Ananda M. Chakrabarty
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Department of Microbiology, University of Illinois College of Medicine, Chicago, USA
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Steven E. Kornguth
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Departments of Neurology and Physiological Chemistry, University of Wisconsin, Madison, USA
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Table of contents (29 papers)
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Biological Detectors
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- Christopher Canfield Green
Pages 15-42
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- Carlos Gitler, Yechiel Shai, Tuvia Bercovoci, Diana Bach, Haim Garty, Israel Rubinstein et al.
Pages 43-61
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- G. Barnard, J. De Boever, Fortune Kohen
Pages 63-78
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- Nicholas F. Almeida, Lemuel B. Wingard Jr.
Pages 89-93
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- Ki-Joon Shon, Patricia Schrader, Yongae Kim, Burkhard Bechinger, Michael Zasloff, Stanley Opella
Pages 109-124
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Molecular Biology in Field Detection
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Front Matter
Pages 125-125
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- Lawrence Grossman, William Athas
Pages 127-140
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- Hermona Soreq, Lewis Neville, Averell Gnatt, Revital Ben-Aziz, Yaron Lapidot-Lifson, Gal Ehrlich et al.
Pages 153-166
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- Paul T. Strickland, Nathaniel Rothman, Miriam C. Poirier
Pages 167-177
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- Sergei Braun, S. Rappoport, S. Shtelzer, R. Zusman, S. Druckmann, D. Avnir et al.
Pages 205-218
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Biological Decontamination
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Front Matter
Pages 219-219
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- Steven Harvey, Joseph J. DeFrank, Daphne Kamely, James J. Valdes, Ananda M. Chakrabarty
Pages 221-230
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About this book
Biotechnology is advancing at a rapid pace with numerous applications in medicine, industry, agriculture and environmental remediation. Recognizing this, government, industrial and academic research and development invest ment in biotechnology has expanded rapidly. The past decade has seen the emergence of applications of this technology with a dual-use potential. Mili tary applications focus on four major areas: biomedical technology, such as vaccine development and medical diagnostics; detection of toxins, chemicals and pathogens; material biotechnology; and biological decontamination, in cluding biodegradation and bioremediation. This conference emphasizes the non-medical applications of biotechnol ogy. The first two sessions focus on the synthesis and properties of molecules that may be used in detectors. The traditional approach to detection of chemical and biological agents relied on the development of specific assays or analyses for known agents. Advances in molecular biology have made possible the production of large quantities of toxins which were previously available in minute quantities, and the molecular engineering of toxins and pathogens with specific pharmacologic and physical-chemical properties. In addition to the traditional approaches to detection of specific known compounds, biotechnology now offers generic approaches to detection. Physiological targets, known as receptors, are primary targets for many drugs and toxins. Similarly, pathogens rely on receptors to gain access to cells. These receptors function as sensitive detectors, generating signals which are transduced and amplified.
Editors and Affiliations
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Research and Laboratory Management, U.S. Army, USA
Daphne Kamely
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Department of Microbiology, University of Illinois College of Medicine, Chicago, USA
Ananda M. Chakrabarty
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Departments of Neurology and Physiological Chemistry, University of Wisconsin, Madison, USA
Steven E. Kornguth
