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Molecular Basis and Thermodynamics of Bioelectrogenesis

  • Book
  • © 1990

Overview

Authors:
  1. E. Schoffeniels

    1. Laboratory of General and Comparative Biochemistry, University of Liège, Liège, Belgium

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  2. D. Margineanu

    1. Laboratory of General and Comparative Biochemistry, University of Liège, Liège, Belgium

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    You can also search for this author in PubMed   Google Scholar

Part of the book series: Topics in Molecular Organization and Engineering (MOOE, volume 5)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-x
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  2. The Description in Physico-Chemical Terms of Nervous System Properties

    • E. Schoffeniels, D. Margineanu
    Pages 1-29

  3. Cell Membranes and Bioelectrogenesis

    • E. Schoffeniels, D. Margineanu
    Pages 30-53

  4. Phenomenological Aspects of Bioelectricity

    • E. Schoffeniels, D. Margineanu
    Pages 54-104

  5. Molecular Approaches of Bioelectricity

    • E. Schoffeniels, D. Margineanu
    Pages 105-124

  6. Puzzle of Nerve Impulse Thermodynamics

    • E. Schoffeniels, D. Margineanu
    Pages 125-142

  7. Thiamine Triphosphate as the Specific Operative Substance in Spike-Generation

    • E. Schoffeniels, D. Margineanu
    Pages 143-150

  8. Merging Electrophysiology and Molecular Approaches

    • E. Schoffeniels, D. Margineanu
    Pages 151-165

  9. Back Matter

    Pages 167-181
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Keywords

About this book

Despite the fact that many years have elapsed since the first microcalorimetric measurements of an action potential were made, there is still among the research workers involved in the study of bioelectrogenesis a complete overlooking of the most fundamental principle governing any biological phenomenon at the molecular scale of dimension. This is surprising, the more so that the techniques of molecular biology are applied to characterize the proteins forming the ionic conducting sites in living membranes. For reasons that are still obscure to us the molecular aspects of bioelectrogenesis are completely out of the scope of the dynamic aspects of biochemistry. Even if it is sometimes recognized that an action potential is a free energy-consuming, entropy-producing process, the next question that should reasonably arise is never taken into consideration. There is indeed a complete evasion of the problem of biochemical energy coupling thus reducing the bioelectrogenesis to only physical interactions of membrane proteins with the electric field: the inbuilt postulate is that no molecular transformations, in the chemical sense, could be involved.

Authors and Affiliations

  • Laboratory of General and Comparative Biochemistry, University of Liège, Liège, Belgium

    E. Schoffeniels, D. Margineanu

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