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Integration in Respiratory Control

From Genes to Systems

  • Book
  • © 2008

Overview

Editors:
  1. Marc J. Poulin

    1. University of Calgary, Calgary, Canada

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    You can also search for this editor in PubMed   Google Scholar

  2. Richard J. A. Wilson

    1. University of Calgary, Calgary, Canada

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    You can also search for this editor in PubMed   Google Scholar

  • Contains the most up-to-date research in cardio-respiratory control
  • Content spans the disciplines of respiratory physiology, neurobiology, modeling, and biomedical engineering
  • Will be of interest to clinicians working with patients with breathing disorders

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 605)

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Table of contents (90 chapters)

  1. Front Matter

    Pages i-xxxi
    Download chapter PDF

  2. Historical and Future Perspectives of the Control of Breathing

    1. History of Measuring O2 and CO2 Responses

      • John W. Severinghaus
      Pages 3-8

    2. J.S. Haldane and Some of His Contributions to Physiology

      • John B. West
      Pages 9-15

    3. Control of the Exercise Hyperpnea: The Unanswered Question

      • Brian J. Whipp
      Pages 16-21

  3. Oxygen Sensing and the Carotid Body

    1. A Peripheral Oxygen Sensor Provides Direct Activation of an Identified Respiratory CPG Neuron in Lymnaea

      • Harold J. Bell, Takuya Inoue, Naweed I. Syed
      Pages 25-29

    2. Environmental Hyperoxia and Development of Carotid Chemoafferent Function

      • Gerald Bisgard, Julie Wenninger, Zunyi Wang, E. Burt Olson Jr.
      Pages 30-34

    3. HSP70 Reduces Chronic Hypoxia-Induced Neural Suppression via Regulating Expression of Syntaxin

      • Guanghe Fei, Conghui Guo, Hong-Shuo Sun, Zhong-Ping Feng
      Pages 35-40

    4. Effect of Systemic Administration of the Nitric Oxide Synthase Inhibitor L-NMMA on the Human Ventilatory Response to Hypoxia

      • Kojiro Ide, Matthew Worthley, Todd Anderson, Marc J. Poulin
      Pages 41-45

    5. Effects of Volatile Anesthetics on Carotid Body Response to Hypoxia in Animals

      • Jaideep J. Pandit, Kevin O’Gallagher
      Pages 46-50

    6. Mutation of the von Hippel-Lindau Gene Alters Human Cardiopulmonary Physiology

      • T. G. Smith, J. T. Brooks, G. M. Balanos, T. R. Lappin, D. M. Layton, D. L. Leedham et al.
      Pages 51-56

    7. Intravenous Endothelin-1 and Ventilatory Sensitivity to Hypoxia in Humans

      • Nick P. Talbot, George M. Balanos, Peter A. Robbins, Keith L Dorrington
      Pages 57-62

    8. Key Roles for AMP-activated Protein Kinase in the Function of the Carotid Body?

      • Christopher N. Wyatt, Selina A. Pearson, Prem Kumar, Chris Peers, D. Grahame Hardie, A. Mark Evans
      Pages 63-68

    9. Stimulatory Actions of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) in Rat Carotid Glomus Cells

      • Fenglian Xu, Frederick W. Tse, Amy Tse
      Pages 69-74

    10. Post-hypoxic Unstable Breathing in the C57BL/6J Mouse: Effects of Acetazolamide

      • Motoo Yamauchi, Jesse Dostal, Kingman P. Strohl
      Pages 75-79

  4. Respiratory Rhythm Generation

    1. Catecholaminergic Modulation of the Respiratory Rhythm Generator in the Isolated Brainstem—Spinal Cord Preparation from Neonatal Rat

      • Akiko Arata, Morimitsu Fujii
      Pages 83-87

    2. What Role Do Pacemakers Play in the Generation of Respiratory Rhythm?

      • Christopher A. Del Negro, Ryland W. Pace, John A. Hayes
      Pages 88-93

    3. Pre-Bötzinger Complex Neurokinin-1 Receptor Expressing Neurons in Primary Cell Culture

      • Shereé M. Johnson
      Pages 94-98

    4. Belt-and-Suspenders as a Biological Design Principle

      • Nicholas M. Mellen
      Pages 99-103

    5. Two Modes of Respiratory Rhythm Generation in the Newborn Rat Brainstem-Spinal Cord Preparation

      • Hiroshi Onimaru, Ikuo Homma
      Pages 104-108

    6. Possible Roles of the Weakly Inward Rectifying K+ Channel Kir4.1 (KCNJ10) in the Pre-Bötzinger Complex

      • Nestoras Papadopoulos, Stefan M. Winter, Kai Härte, Melanie Kaiser, Clemens Neusch, Swen Hülsmann
      Pages 109-113
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Keywords

About this book

Like the geological treasures that surely must lie below the Athabasca glacier, some of the answers to key questions about the control of respiration remain buried. But bit by bit, year by year the ice is melting and perhaps in some areas the rocks are starting to be revealed. With a mission to advance our understanding of the emerging th th gems of respiration, the X Oxford Conference was held between 19–24 September (2006) next to the turquoise and tranquil waters of Lake Louise, in the middle of Banff National Park, Alberta, Canada. Since its inauguration 30 years ago in Oxford, the Oxford Conference on mo- ling and control of breathing has been held every three years in locations spanning the globe (a list of past conferences and publications that have emerged is included in the pages that follow). The series has provided key opportunities for respiratory scientists to meet with colleagues, discuss recent advances and celebrate their field. The 2006 Lake Louise meeting was Canada’s second Oxford Conference; the th previous Canadian meeting (the VII Oxford Conference) was held in 1997 at the Grandview Inn in Huntsville (Ontario) and was chaired by Richard Hughson, David Cunningham and Jim Duffin.

Reviews

From the reviews:

"This excellent resource for researchers working in the area of respiratory control is full of original work presented at the 10th Oxford conference held in 2006 in Lake Louise, Alberta, Canada. … Researchers and clinicians in pulmonary and sleep medicine will find this book valuable, as will respiratory physiologists, students, and trainees in pulmonary diseases. … This is a good referral resource for researchers who are actively working in the field of respiratory control." (K. P. Ravikrishnan, Doody’s Review Service, October, 2008)

Editors and Affiliations

  • University of Calgary, Calgary, Canada

    Marc J. Poulin, Richard J. A. Wilson

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