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  • © 2013

Principles of Statistical Genomics

Authors:

  • covers microarray data analysis, which is absent in both competing books in addition to QTL mapping
  • introduces Bayesian method, which was not available in both competing books
  • uses more rigorous mathematical approaches to derive the statistical methods
  • Includes supplementary material: sn.pub/extras

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xv
  2. Genetic Linkage Map

    1. Front Matter

      Pages 1-1
    2. Map Functions

      • Shizhong Xu
      Pages 3-10
    3. Recombination Fraction

      • Shizhong Xu
      Pages 11-22
    4. Genetic Map Construction

      • Shizhong Xu
      Pages 23-33
    5. Multipoint Analysis of Mendelian Loci

      • Shizhong Xu
      Pages 35-49
  3. Analysis of Quantitative Traits

    1. Front Matter

      Pages 51-51
    2. Basic Concepts of Quantitative Genetics

      • Shizhong Xu
      Pages 53-60
    3. Major Gene Detection

      • Shizhong Xu
      Pages 61-78
    4. Segregation Analysis

      • Shizhong Xu
      Pages 79-93
    5. Interval Mapping

      • Shizhong Xu
      Pages 109-129
    6. Interval Mapping for Ordinal Traits

      • Shizhong Xu
      Pages 131-149
    7. Mapping Segregation Distortion Loci

      • Shizhong Xu
      Pages 151-170
    8. QTL Mapping in Other Populations

      • Shizhong Xu
      Pages 171-185
    9. Random Model Approach to QTL Mapping

      • Shizhong Xu
      Pages 187-207
    10. Mapping QTL for Multiple Traits

      • Shizhong Xu
      Pages 209-222
    11. Bayesian Multiple QTL Mapping

      • Shizhong Xu
      Pages 223-256
    12. Empirical Bayesian QTL Mapping

      • Shizhong Xu
      Pages 257-279
  4. Microarray Data Analysis

    1. Front Matter

      Pages 281-281

About this book

Statistical genomics is a rapidly developing field, with more and more people involved in this area. However, a lack of synthetic reference books and textbooks in statistical genomics has become a major hurdle on the development of the field. Although many books have been published recently in bioinformatics, most of them emphasize DNA sequence analysis under a deterministic approach.

Principles of Statistical Genomics synthesizes the state-of-the-art statistical methodologies (stochastic approaches) applied to genome study. It facilitates understanding of the statistical models and methods behind the major bioinformatics software packages, which will help researchers choose the optimal algorithm to analyze their data and better interpret the results of their analyses. Understanding existing statistical models and algorithms assists researchers to develop improved statistical methods to extract maximum information from their data.

Resourceful and easy to use,Principles of Statistical Genomics is a comprehensive reference for researchers and graduate students studying statistical genomics. 

Reviews

From the reviews:

“The book was compiled from a collection of lecture notes for a statistical genomics course offered to University California Riverside graduate students by the author. It can be used as a textbook for graduate students in statistical genomics, but also by researchers as a reference book. … For advanced readers of this very modern book in a new field of biometrics, they can choose to read any particular chapters as they desire in this multidisciplinary area.” (T. Postelnicu, zbMATH, Vol. 1276, 2014)

Authors and Affiliations

  • Department of Botany and Plant Sciences, University of California, Riverside, USA

    Shizhong Xu

About the author

Shizhong Xu, PhD
University of California, Department of Botany and Plant Sciences, Riverside, CA, USA

Bibliographic Information

  • Book Title: Principles of Statistical Genomics

  • Authors: Shizhong Xu

  • DOI: https://doi.org/10.1007/978-0-387-70807-2

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2013

  • Hardcover ISBN: 978-0-387-70806-5Published: 10 September 2012

  • Softcover ISBN: 978-1-4899-9404-2Published: 15 October 2014

  • eBook ISBN: 978-0-387-70807-2Published: 13 September 2012

  • Edition Number: 1

  • Number of Pages: XVI, 428

  • Topics: Plant Genetics and Genomics, Animal Genetics and Genomics

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access