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Cardiac Mechanotransduction

  • Book
  • © 2007

Overview

Authors:
  1. Matti Weckström

    1. Department of Physical Sciences Division of Biophysics, University of Oulu, Oulu, Finland
      Biocenter Oulu, University of Oulu, Oulu, Finland

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  2. Pasi Tavi

    1. Biocenter Oulu, University of Oulu, Oulu, Finland
      Department of Physiology Division of Biophysics, University of Oulu, Oulu, Finland

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  • Covers extensively cardiac mechanotransduction, a process whereby stretch or volume loading of the heart changes its function

  • Has strong multidisciplinary appeal

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Table of contents (9 chapters)

  1. Front Matter

    Pages I-XII
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  2. The Mechanosensory Heart

    • Matti Weckström, Pasi Tavi
    Pages 1-7

  3. Origin of Mechanotransduction

    • Clive M. Baumgarten
    Pages 8-27

  4. The Role of the Sarcomere and Cytoskeleton in Cardiac Mechanotransduction

    • Sarah C. Calaghan, Ed White
    Pages 28-47

  5. Mechanoelectric Transduction/Feedback: Physiology and Pathophysiology

    • Max J. Lab
    Pages 48-77

  6. Mechanotransduction in Cardiac Remodeling and Heart Failure

    • Jeffrey H. Omens, Andrew D. McCulloch, Ilka Lorenzen-Schmidt
    Pages 78-92

  7. Second Messenger Systems Involved in Heart Mechanotransduction

    • Hiroshi Hasegawa, Hiroyuki Takano, Yunzeng Zou, Hiroshi Akazawa, Issei Komuro
    Pages 93-105

  8. The Role of Adrenoceptors in Mechanotransduction

    • Klaus-Dieter Schlüter, Hans Michael Piper, Sibylle Wenzel
    Pages 106-119

  9. Intracellular Signaling Through Protein Kinases in Cardiac Mechanotransduction

    • Peter H. Sugden
    Pages 120-133

  10. Mechanotransduction of the Endocrine Heart

    • Sampsa Pikkarainen, Heikki Tokola, Heikki Ruskoaho
    Pages 134-144

  11. Back Matter

    Pages 145-147
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Keywords

About this book

For about hundred years the investigation of heart physiology has had one central guiding principle, the "law" of Frank and Starling. This connects the return of blood into the heart and the blood pressure with cardiac con­ traction force. The "law" does it in a way that enables the cardiovascular system to react to perturbations without major malfunctions. This book is a compilation of reviews of prominent scientists on this subject. The differ­ ence of the original formulation of the Frank-Starling principle is that mechanotransduction is the central theme that leads the reader through the book. Since the discovery of the "law" the scope of topics related to this subject has broadened enormously, as can be seen easily by glancing at the contents of this book. Mechanotransduction in the heart has many faces that range from molecules to humans and their diseases. We editors hope that the large amount of knowledge compressed into the book's chapters forms a balanced treatment and that the text is easily approached by all who want to know what cardiac mechanotransduction is about. Matti Weckstrom and Pasi Tavi Oulu, Finland June 16. 2006 Ackno^vledgments The editors are grateful to all authors for their magnificent contributions and for their patience during compiling this book. This work was supported by the University of Oulu, the Biocenter Oulu and the Academy of Finland.

Authors and Affiliations

  • Department of Physical Sciences Division of Biophysics, University of Oulu, Oulu, Finland

    Matti Weckström

  • Biocenter Oulu, University of Oulu, Oulu, Finland

    Matti Weckström, Pasi Tavi

  • Department of Physiology Division of Biophysics, University of Oulu, Oulu, Finland

    Pasi Tavi

Bibliographic Information

  • Book Title: Cardiac Mechanotransduction

  • Authors: Matti Weckström, Pasi Tavi

  • DOI: https://doi.org/10.1007/978-0-387-48868-4

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag New York 2007

  • Hardcover ISBN: 978-0-387-48867-7Published: 21 December 2006

  • Softcover ISBN: 978-1-4419-2373-8Published: 29 October 2010

  • eBook ISBN: 978-0-387-48868-4Published: 22 December 2007

  • Edition Number: 1

  • Number of Pages: XII, 159

  • Number of Illustrations: 46 b/w illustrations

  • Topics: Human Physiology, Cell Biology, Cardiology

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