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Rho GTPases

  • Book
  • © 2004

Overview

Part of the book series: Molecular Biology Intelligence Unit (MBIU)

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About this book

Members of the Rho family of small GTP-binding proteins (GTPases) are key signal transduction proteins that mediate signals initiated by growth factors, cytokines and cell adhesion proteins. Our knowledge about Rho GTPases has rapidly expanded over the past several years and Rho GTPases is the first book to provide a comprehensive overview of the regulation and functions of this important class of proteins.
This book includes several chapters dedicated to the review of various classes of proteins that control the localization and activation state of Rho GTPases. Additional chapters discuss the wide range of biological functions that are controlled by Rho GTPases, including the organization of the actin cytoskeleton, cell proliferation and cell motility.
Rho GTPases is essential reading for cell and molecular biologists, biochemists and geneticists. The critical roles of Rho family members in cancer and inflammatory diseases makes Rho GTPases also an invaluable guide for clinical investigators and pharmacologists.

Editors and Affiliations

  • Jewish Research Institute Center for Oncology & Cell Biology, Manhasset, USA

    Marc H. Symons

Bibliographic Information

  • Book Title: Rho GTPases

  • Editors: Marc H. Symons

  • Series Title: Molecular Biology Intelligence Unit

  • Publisher: Springer New York, NY

  • Copyright Information: Springer-Verlag US 2004

  • Hardcover ISBN: 978-0-306-47992-2Published: 31 May 2004

  • Series ISSN: 1431-0414

  • Edition Number: 1

  • Number of Pages: XII, 236

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