Oxygen Transport To Tissue XXIII

1. Front Matter

   Pages i-xviii

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2. Tumor Biology And Physiology

   1. The Role of Tumor Oxygenation in Vascular and Clinical Response to Angiogenesis Inhibition

      • Michael S. Gee, William M. F. Lee

      Pages 1-5

   2. Comparison of Fluctuations of Oxygen Tension in FSA, 9L, and R3230AC Tumors in Rats

      • L. Isabel Cárdenas-Navia, Rod Braun, Kristina Lewis, Mark W. Dewhirst

      Pages 7-12

   3. Effect of Carbogen-Breathing on Redox Status of the RIF-1 Tumor

      • Govindasamy Ilangovan, Haiquan Li, Jay L. Zweier, Periannan Kuppusamy

      Pages 13-17

   4. Evaluation of Microregional Variations in Tumor Hypoxia Following the Administration of Endostatin

      • Bruce M. Fenton, Scott F. Paoni, Brian K. Beauchamp, Baohuong Tran, Liang Li, Ivan Ding et al.

      Pages 19-24

   5. Effect of Hydralazine on Blood Flow, Oxygenation, and Interstitial Fluid Pressure in Subcutaneous Tumors

      • Tomaž Jarm, Blaž Podobnik, Damijan Miklavčič, Gregor Serša

      Pages 25-29

   6. Oxygenation of Cervix Cancers: Impact of Clinical and Pathological Parameters

      • Michael Höckel, Peter Vaupel

      Pages 31-35

   7. Quantitative Spatial Analysis of Hypoxia and Vascular Perfusion in Tumor Sections

      • E. Paul Wileyto, Sydney M. Evans, Theresa M. Busch, Cameron J. Koch

      Pages 37-43

   8. Tumor Oxygenation and Its Relevance to Tumor Physiology and Treatment

      • Peter Vaupel, Michael Höckel

      Pages 45-49

   9. Mechanisms Underlying Hypoxia Development in Tumors

      • Mark W. Dewhirst

      Pages 51-56

   10. Lack of Association Between Tumor Hypoxia, Glut-1 Expression and Glucose Uptake in Experimental Sarcomas

       • Oliver Thews, Debra K. Kelleher, Norbert Esser, Stephan Kraus, Peter Vaupel

       Pages 57-61

   11. The Impact of Tissue Microenvironment on Treatment Simulation

       • Alexandru Daşu, Juliana Denekamp

       Pages 63-67

   12. Evidence for and Against Hypoxia as the Primary Cause of Tumor Aggressiveness

       • Paul Okunieff, Ivan Ding, Peter Vaupel, Michael Höckel

       Pages 69-75

   13. Characterization of Human Gc Protein- Derived Macrophage Activation Factor (GcMAF) and Its Functional Role in Macrophage Tumoricidal Activity

       • Saharuddin B. Mohamad, Hitoshi Hori, Hideko Nagasawa, Kenji Usui, Yoshihiro Uto

       Pages 77-82

3. Blood Physiology And Blood Substitutes

   1. Effect of Hemoglobin Solutions as Hemodiluents on Capillary Oxygen Tension

      • Roland N. Pittman, Kristin B. Miller, Peter H. Tait

      Pages 83-88

   2. Different Efficacy in Vitro of Hemoglobin Based Oxygen Carriers and Red Cells

      • E. Bucci, H. E. Kwansa, T. L. Watts, A. Fasano

      Pages 89-92

   3. A Novel Blood Transfusant Candidate: Intact Human Erythrocytes Containing Hemoglobin Exclusively Nitrosylated in the α-Subunits

      • Antonio Tsuneshige, Takashi Yonetani

      Pages 93-99

   4. The Contribution of Hemoglobin to Oxygen Transport in the Microcrustacean Daphnia Magna

      • Ralph Pirow

      Pages 101-107

   5. Modifications of Red Blood Cell Shape and Glycoproteins Membrane Content in Septic Patients

      • Michael Piagnerelli, Jean-Louis Vincent, Karim Zouaoui Boudjeltia, Danny Brohee, Michel Vanhaeverbeek

      Pages 109-114

   6. Fiber Optic Immunosensors for Cardiovascular Disease Diagnosis

      • Hyun J. Kwon, Kyung A. Kang, Stephen C. Peiper

      Pages 115-119

The ISOTT 2001 local organizing committee was pleased to welcome over 140 delegates from around the world to the 29th annual general meeting of the International Society for Oxygen Transport to Tissue. The meeting was held in historic Philadelphia, USA, on the campus of the University of Pennsylvania from August 11 to 15, 2001. In the tradition of ISOTT, the conference was a total immersion experience. Attendees were encouraged to eat together and spend their evenings relaxing together in a style that maximized exchange of ideas and interactions of younger scientists with their more senior colleagues. Delegates participated in a total of 122 presentations including poster displays, selected oral presentations, seminars by invited speakers and a round table discussion. In choosing invited speakers and oral presenters, special emphasis was placed on methods for oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. All of the manuscripts contained in this volume underwent both an editorial and scientific review, and only those meeting both criteria have been published. However, while all efforts have been made to eliminate editorial errors, some have undoubtedly been overlooked, for which the editors apologize.

• blood cell
• cells
• computer simulation
• erythrocyte
• metabolism
• physiology
• proteins
• tissue

• University of Pennsylvania, Philadelphia, USA

  David F. Wilson, Sydney M. Evans, John Biaglow, Anna Pastuszko

Policies and ethics