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Structure-Function Relationships of Human Pathogenic Viruses

  • Book
  • © 2002

Overview

Editors:
  1. Andreas Holzenburg

    1. Microscopy and Imaging Center Department of Biology Department of Biochemistry and Biophysics, Texas A&M University, College Station

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  2. Elke Bogner

    1. Institut für Klinische and Molekulare Virologie, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xvii
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  3. Viral replication

    1. Viral RNA-directed Polymerases: Structure and Function Relationships

      • Joachim Jäger, Janice D Pata
      Pages 57-88

    2. Marburg Virus Replication and Nucleocapsid Formation: Different Jobs, Same Players

      • Elke Mühlberger, Stephan Becker
      Pages 89-107

  4. Viral determinants for capsid formation and packaging

    1. Packaging DNA into Herpesvirus Capsids

      • Jay C. Brown, Michael A. McVoy, Fred L. Homa
      Pages 111-153

    2. From Concatemeric DNA into Unit-length Genomes—a Miracle or Clever Genes?

      • Andreas Holzenburg, Elke Bogner
      Pages 155-170

  5. Determinants for viral maturation

    1. Role of Envelope Proteins in Measles Virus Assembly

      • Andrea Maisner
      Pages 173-193

    2. The Predominant Varicella-zoster Virus gE and gI Glycoprotein Complex

      • Charles Grose
      Pages 195-223

    3. Expression Strategy and Functions of the Filoviral Glycoproteins

      • Viktor E. Volchkov, Heinz Feldmann
      Pages 225-251

  6. Pathogenesis

    1. Prions

      • Anne Bellon, Martin Vey
      Pages 255-294

    2. Human Immunodeficiency Virus From Virus Structure to Pathogenesis

      • Hans R. Gelderblom, Klaus Boller
      Pages 295-330

    3. The Role of Hemagglutinin and Neuraminidase in Influenza Virus Pathogenicity

      • Ralf Wagner, Anke Feldmann, Thorsten Wolff, Stephan Pleschka, Wolfgang Garten, Hans-Dieter Klenk
      Pages 331-345

  7. Viral oncogenesis

    1. Rhadinovirus Pathogenesis

      • Armin Ensser, Frank Neipel, Helmut Fickenscher
      Pages 349-429

    2. Interaction of Papillomaviral Oncoproteins with Cellular Factors

      • Sigrun Smola-Hess, Herbert J. Pfister
      Pages 431-461

  8. Defense mechanisms

    1. Cytomegalovirus Glycoproteins Interacting with MHC Class I Molecules and the MHC-encoded Peptide Transporter

      • Albert Zimmermann, Anne Halenius, Hartmut Hengel
      Pages 465-484

    2. Regulation of Cellular Genes by Cytomegalovirus

      • Mark F. Stinski, Yoon-Jae Song
      Pages 485-507

  9. Back Matter

    Pages 509-528
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Keywords

About this book

Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis.

Furthermore Structure-Function Relationships of Human Pathogenic Viruses illustrates in a single volume the fundamental processes involved in viral life cycles using up-to-date information from research laboratories around the world. Knowledge of these processes is crucial to develop rationales for the design of future drugs. The timeliness of the data and the comprehensive yet concise approach this book takes in order to present the world of viral pathogens should make it a frontrunner in higher education and R&D.

Editors and Affiliations

  • Microscopy and Imaging Center Department of Biology Department of Biochemistry and Biophysics, Texas A&M University, College Station

    Andreas Holzenburg

  • Institut für Klinische and Molekulare Virologie, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

    Elke Bogner

Bibliographic Information

  • Book Title: Structure-Function Relationships of Human Pathogenic Viruses

  • Editors: Andreas Holzenburg, Elke Bogner

  • DOI: https://doi.org/10.1007/b111763

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2002

  • Hardcover ISBN: 978-0-306-46768-4Published: 30 April 2002

  • Softcover ISBN: 978-1-4757-8226-4Published: 03 May 2013

  • eBook ISBN: 978-0-306-47650-1Published: 08 May 2007

  • Edition Number: 1

  • Number of Pages: XIX, 528

  • Number of Illustrations: 66 b/w illustrations, 7 illustrations in colour

  • Topics: Virology, Parasitology, Biochemistry, general, Tropical Medicine

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