Genomic Diversity

1. Front Matter

   Pages i-viii

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2. Classical to Molecular Polymorphisms

   • S. S. Papiha, S. S. Mastana

   Pages 1-21

3. Variability in nDNA, mtDNA, and Proteins

   • Mara H. Hutz, Sidia M. Callegari-Jacques, Maria C. Bortolini, Francisco M. Salzano

   Pages 23-32

4. Genetic Diversity Among Five Native American Tribes of Colombia

   • F. D. Guarino, L. Federle, R. A. H. van Oorschot, I. Briceno, J. E. Bernal, S. S. Papiha et al.

   Pages 33-51

5. Trinucleotide Repeats, Genetic Instability and Variation in the Human Genome

   • Ranjan Deka, Ranajit Chakraborty

   Pages 53-64

6. Y-Chromosomal DNA Markers

   • Chris Tyler-Smith

   Pages 65-73

7. On the Genetic Origin of the Turks

   • Burkhard Rolf, Arne Röhl, Peter Forster, Bernd Brinkmann

   Pages 75-82

8. The Origins of Pakistani Populations

   • S. Q. Mehdi, R. Qamar, Q. Ayub, S. Khaliq, A. Mansoor, M. Ismail et al.

   Pages 83-90

9. The Use of Y-Chromosomal DNA Variation to Investigate Population History

   • Tatiana Zerjal, Arpita Pandya, Fabrício R. Santos, Raju Adhikari, Eduardo Tarazona, Manfred Kayser et al.

   Pages 91-101

10. A Mitochondrial DNA Database

    • P. Francalacci, R. Montiel, A. Malgosa

    Pages 103-119

11. The Trans-Caucasus and the Expansion of the Caucasoid-Specific Human Mitochondrial DNA

    • Ene Metspalu, Toomas Kivisild, Katrin Kaldma, Jüri Parik, Maere Reidla, Kristiina Tambets et al.

    Pages 121-133

12. The Place of the Indian Mitochondrial DNA Variants in the Global Network of Maternal Lineages and the Peopling of the Old World

    • Toomas Kivisild, Katrin Kaldma, Mait Metspalu, Jüri Parik, Surinder Papiha, Richard Villems

    Pages 135-152

13. Mitochondrial DNA Variation in the Southwest Pacific

    • D. Andrew Merriwether, Frederika A. Kaestle, Babette Zemel, George Koki, Charles Mgone, Michael Alpers et al.

    Pages 153-181

14. Molecular Anthropology

    • Connie J. Kolman

    Pages 183-200

15. Interspersed Repeat Insertion Polymorphisms for Studies of Human Molecular Anthropology

    • Prescott L. Deininger, Stephen T. Sherry, Gregory Risch, Chadwick Donaldson, Myles B. Robichaux, Himla Soodyall et al.

    Pages 201-212

16. Worldwide Distribution of a PolymorphicAluInsertion in the Progesterone Receptor Gene

    • Adriana Antúnez-de-Mayolo, Gabriela Antúnez-de-Mayolo, Emmanuel Thomas, Erika P. Reategui, Michael D. Brown, Rene J. Herrera

    Pages 213-222

17. Statistical Issues Regarding the Use of Microsatellite Loci for Molecular Anthropological Studies

    • Ranajit Chakraborty

    Pages 223-235

18. Epilogue

    • Surinder S. Papiha, Ranjan Deka, Ranajit Chakraborty

    Pages 237-239

19. Back Matter

    Pages 241-246

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One of the major themes of human population genetics is assaying genetic variation in human populations. The ultimate goal of this objective is to understand the extent of genetic diversity and the use of this knowledge to reconstruct our evolutionary history. The discipline had undergone a revolutionary transition with the advent of molecular techniques in the 1980s. With this shift, statistical methods have also been developed to perceive the biological and molecular basis of human genetic variation.
Using the new perspectives gained during the above transition, this volume describes the applications of molecular markers spanning the autosomal, Y-chromosomal and mitochondrial genome in the analysis of human diversity in contemporary populations. This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume.

• Chromosom
• DNA
• chromosome
• evolution
• genetics

• University of Newcastle upon Tyne, Newcastle upon Tyne, UK

  Surinder S. Papiha

• University of Cincinnati, Cincinnati, USA

  Ranjan Deka

• University of Texas Health Science Center, Houston, USA

  Ranajit Chakraborty

Policies and ethics