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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-ix
  2. Synthesis and Activity of Platinum Compounds

    1. NMR Spectroscopy of Platinum Drugs: From DNA to Body Fluids

      • Kevin J. Barnham, Susan J. Berners-Price, Zijian Guo, Piedad del Socorro Murdoch, Peter J. Sadler
      Pages 1-16
    2. Trans-Diamminedichloroplatinum (II) Is Not an Antitumor Drug: Why?

      • Rozenn Dalbiès, Marc Boudvillain, Marc Leng
      Pages 17-25
    3. Iminoethers as Carrier Ligands: A Novel trans-Platinum Complex Possessing in Vitro and in Vivo Antitumour Activity

      • Mauro Coluccia, Maria A. Mariggiò, Angela Boccarelli, Francesco Loseto, Nicola Cardellicchio, Paola Caputo et al.
      Pages 27-35
    4. Orally Active DACH-Pt (IV) Compounds

      • Yoshinori Kidani, Ryoichi Kizu, Motoichi Miyazaki, Masahide Noji, Akio Matsuzawa, Yasutaka Takeda et al.
      Pages 43-51
  3. Clinical Pharmacology

    1. Pharmacokinetic — Pharmacodynamic Relationships

      • Pierre Canal, Etienne Chatelut
      Pages 53-66
    2. Clinical Pharmacology of Carboplatin Administered in Alternating Sequence with Paclitaxel in Patients with Non-Small Cell Lung Cancer: A European Cancer Centre (ECC) Study

      • L. J. C. van Warmerdam, M. T. Huizing, G. Giaccone, P. J. M. Bakker, J. B. Vermorken, P. E. Postmus et al.
      Pages 67-82
    3. The Clinical Development of the Oral Platinum Anticancer Agent JM216

      • Ian Judson, Mark McKeage, Janet Hanwell, Claire Berry, Prakash Mistry, Florence Raynaud et al.
      Pages 83-89
  4. Biochemistry and Molecular Pharmacology

    1. Membrane Transport of Platinum Compounds

      • Gerrit Los, Dennis Gately, Michael L. Costello, Franz Thiebaut, Peter Naredi, Stephen B. Howell
      Pages 91-105
    2. Detection of Adducts Formed upon Treatment of DNA with Cisplatin and Carboplatin

      • Anne Marie J. Fichtinger-Schepman, Marij J. P. Welters, Helma C. M. van Dijk-Knijnenburg, Marianne L. T. van der Sterre, Michael J. Tilby, Frits Berends et al.
      Pages 107-119
    3. Detection of Platinum Lesions at the Nucleotide Level in Cells using Single Strand Ligation PCR

      • John A. Hartley, Robert L. Souhami, Keith A. Grimaldi
      Pages 121-130
    4. Combination Therapy with Cisplatinum and EGF Receptor Blockade

      • John Mendelsohn, Zhen Fan, Jose Baselga
      Pages 155-163
  5. Clinical Studies

    1. Oxaliplatin: Update on a Active and Safe Dach Platinum Complex

      • P. Soulié, E. Raymond, J. L. Misset, E. Cvitkovic
      Pages 165-174
    2. Phase I and II Studies with Lobaplatin

      • H. H. Fiebig
      Pages 181-186
    3. Phase I Trials of Ormaplatin (NSC 363812)

      • Michaele C. Christian
      Pages 187-192
    4. 254-S, NK121 and TRK710

      • Makoto Ogawa
      Pages 193-197

Editors and Affiliations

  • Free University, Amsterdam, The Netherlands

    H. M. Pinedo

  • Netherlands Cancer Institute, Amsterdam, The Netherlands

    J. H. Schornagel

Bibliographic Information

  • Book Title: Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2

  • Editors: H. M. Pinedo, J. H. Schornagel

  • DOI: https://doi.org/10.1007/978-1-4899-0218-4

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1996

  • Hardcover ISBN: 978-0-306-45287-1Published: 30 April 1996

  • Softcover ISBN: 978-1-4899-0220-7Published: 20 June 2013

  • eBook ISBN: 978-1-4899-0218-4Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: X, 358

  • Topics: Oncology, Immunology, Biochemistry, general

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access